DDR2 anticorps (AA 801-855)

N° du produit ABIN6654123

Cet anticorps Lapin Polyclonal détecte spécifiquement DDR2 dans WB, ELISA et IHC (p). Il présente une réactivité envers Souris et Rat.

Aperçu rapide pour DDR2 anticorps (AA 801-855) (ABIN6654123)

Antigène: DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DDR2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-DDR2 anticorps

Épitope: AA 801-855

Purification: Antigen affinity purified

Immunogène: Amino acids T801-E855 from the human protein were used as the immunogen for the DDR2 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the DDR2 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,IHC (FFPE): 2-3 μg/mL,Direct ELISA: 0.1-0.5 μg/mL (recombinant human protein)

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the DDR2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur DDR2

Antigène: DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))

Autre désignation: DDR2

Sujet: Discoidin domain-containing receptor 2, also known as CD167b (cluster of differentiation 167b), is a protein that in humans is encoded by the DDR2 gene. This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironment. The encoded protein is a collagen-induced receptor that activates signal transduction pathways involved in cell adhesion, proliferation, and extracellular matrix remodeling. This protein is expressed in numerous cell types and may alos be involved in wound repair and regulate tumor growth and invasiveness. Mutations in this gene are the cause of short limb-hand type spondylometaepiphyseal dysplasia.

UniProt: Q16832

Pathways: Signalisation RTK