ADRP anticorps
Aperçu rapide pour ADRP anticorps (ABIN6654241)
Antigène
Voir toutes ADRP (PLIN2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Purification
- Purified
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Pureté
- Protein A affinity chromatography
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Immunogène
- A portion of amin acids 249-376 from the human protein were used as the immunogen for this recombinant Adipophilin antibody.
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Isotype
- IgG kappa
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Indications d'application
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Titering of the recombinant Adipophilin antibody may be required for optimal performance.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. ELISA: order formulation without BSA for coating,Immunohistochemistry (FFPE): 1-2 μg/mL,Prediluted IHC only format: incubate for 30 min at RT (1),Western blot: 1-2 μg/mL -
Restrictions
- For Research Use only
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- The recombinant Adipophilin antibody (with azide) can be stored at 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- ADRP (PLIN2) (Perilipin 2 (PLIN2))
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Autre désignation
- Adipophilin / Perilipin 2 / ADRP / PLIN2
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Sujet
- Recognizes a protein of 48 kDa, which is identified as Adipophilin. It belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases.
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Pathways
- Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism
Antigène
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