RAC1 anticorps (full length)

N° du produit ABIN6654501

Cet anticorps Souris Monoclonal détecte spécifiquement RAC1 dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour RAC1 anticorps (full length) (ABIN6654501)

Antigène: RAC1

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RAC1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: CPTC-RAC1-1

Détail du produit anti-RAC1 anticorps

Épitope: full length

Fonction: RAC1 Antibody (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogène: Full length recombinant human protein was used as the immunogen for this RAC1 antibody.

Isotype: IgG1

Information d'application

Indications d'application: Optimal dilution of the RAC1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the RAC1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur RAC1

Antigène: RAC1

Sujet: Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity in macrophages (By similarity). Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly. Rac1 has been demonstrated to play a critical role in tumor progression of human colorectal adenocarcinoma cells. In one study, overexpression of Rac1 accelerated the tumorigenic process, whereas Rac1 inhibition completed suppressed tumor formation.

UniProt: P63000

Pathways: Signalisation WNT, Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Thromboxane A2 Receptor Signaling, VEGF Signaling