Recombinant IL3RA anticorps (AA 26-171)

N° du produit ABIN6654876

Cet anticorps Lapin Monoclonal détecte spécifiquement IL3RA dans ELISA et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant IL3RA anticorps (AA 26-171) (ABIN6654876)

Antigène: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp IL3RA est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: IL3RA-2947R

Détail du produit anti-IL3RA anticorps

Épitope: AA 26-171

Fonction: Recombinant CD123 Antibody / IL3RA

Purification: Protein A affinity chromatography

Immunogène: A portion of amino acids 26-171 was used as the immunogen for the recombinant CD123 antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal dilution of the recombinant CD123 antibody should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the recombinant CD123 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur IL3RA

Antigène: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Autre désignation: CD123

Sujet: CD123 is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudo-autosomal region on chromosomes X or Y.

UniProt: P26951

Pathways: Signalistation JAK/STAT