IL3RA anticorps (AA 26-171)

N° du produit ABIN6654878

Cet anticorps anti-IL3RA est un anticorps Lapin Monoclonal détectant IL3RA dans IHC (p). Adapté pour Humain.

Aperçu rapide pour IL3RA anticorps (AA 26-171) (ABIN6654878)

Antigène: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp IL3RA est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: IL3RA-2947R

Détail du produit anti-IL3RA anticorps

Épitope: AA 26-171

Purification: Purified

Pureté: Protein A affinity chromatography

Immunogène: A portion of amino acids 26-171 was used as the immunogen for the recombinant CD123 antibody.

Isotype: IgG kappa

Information d'application

Indications d'application: Optimal dilution of the recombinant CD123 antibody should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 0.25-0.5 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)

Restrictions: For Research Use only

Stockage

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the recombinant CD123 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur IL3RA

Antigène: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Autre désignation: IL3RA / CD123

Sujet: CD123 is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudo-autosomal region on chromosomes X or Y.

Pathways: Signalistation JAK/STAT