Recombinant CD63 anticorps (full length)

N° du produit ABIN6654892

L’anticorps anti-CD63 Monoclonal Lapin est utilisé pour la détection de CD63 dans des échantillons de Humain. Il a été validé pour FACS et IHC (p).

Aperçu rapide pour Recombinant CD63 anticorps (full length) (ABIN6654892)

Antigène: CD63

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CD63 est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: LAMP3-2990R

Détail du produit anti-CD63 anticorps

Épitope: full length

Fonction: Recombinant CD63 Antibody / LAMP-3 (azide and preservative free)

Purification: Protein A affinity chromatography

Immunogène: Recombinant human full-length protein was used as the immunogen for the recombinant CD63 antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal dilution of the recombinant CD63 antibody should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the recombinant CD63 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur CD63

Antigène: CD63

Autre désignation: CD63

Sujet: This mAb recognizes protein of 26 kDa-60 kDa, which is identified as CD63/LAMP-3. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63/LAMP-3 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. It is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63/LAMP-3 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. Deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.

UniProt: P08962