EPH Receptor B2 anticorps (pTyr331)

N° du produit ABIN6655037

N° du produit (Fournisseur): 600-401-d37

Cet anticorps anti-EPH Receptor B2 est un anticorps Lapin Polyclonal détectant EPH Receptor B2 dans WB et ELISA. Adapté pour Poulet.

Aperçu rapide pour EPH Receptor B2 anticorps (pTyr331) (ABIN6655037)

Antigène: EPH Receptor B2 (EPHB2)

Reactivité: Poulet

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPH Receptor B2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-EPH Receptor B2 anticorps

Épitope: pTyr331

N° du produit (Fournisseur): 600-401-d37

Fournisseur: Rockland

Fonction: EphrinB phospho Y331 Antibody

Réactivité croisée (Details): Anti-EphrinB pY331 antibody is directed against rat EphrinB.

Purification: Anti-EphrinB pY331 antibody was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities.

Immunogène: Anti-EphrinB pY331 Antibody was produced in rabbit by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Tyr331 Xenopus EphrinB conjugated to KLH.

Isotype: IgG

Information d'application

Indications d'application:

ELISA_Dilution: 1:10,000

Western_Blot_Dilution: 1:1000

Commentaires:

Anti-EphrinB pY331 Antibody is tested for use in ELISA and Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 46 kDa in size corresponding to EphrinB protein phosphorylated at Tyr331 in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur EPH Receptor B2

Antigène: EPH Receptor B2 (EPHB2)

Autre désignation: EPHB2

Sujet:

Synonyms: Ephrin type-B receptor 2, EPH-like kinase 5, EK5

Background: EphrinB Antibody detects EphrinB proteins which are thought to play key roles in cellular functions as diverse as neuronal migration and blood vessel development. EphrinB molecules expressed at the membrane surface bind to the EphB family receptors on target cells during cell-to cell contact. This interaction leads to cell signaling in the target cell but also generates a reverse signal in the cell expressing EphrinB on its surface. This reverse signaling event is thought to be critical for vessel maturation and neuronal development. Importantly, tyrosine phosphorylation of EphrinB is thought to be a critical component of this reverse signaling event. Recent work demonstrated that Tyr331 of EphrinB was phosphorylated in HEK293 cells after timulation by the soluble EphB2 receptor tyrosine kinase. Anti-EphrinB pY331 Antibody is ideal for investigators involved in Cell Migration, Cell Division, Cell Signaling and Neuroscience.

Gene Name: EPHB2

ID gène: 396513

NCBI Accession: NP_996834

UniProt: P28693

Pathways: Signalisation RTK, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins