CD80 anticorps (APC)

N° du produit ABIN6655080

N° du produit (Fournisseur): 200-326-n74

Cet anticorps Souris Monoclonal détecte spécifiquement CD80 dans FACS, WB et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour CD80 anticorps (APC) (ABIN6655080)

Antigène: CD80

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD80 est conjugé à/à la APC

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC)

Clone: 2D10

Détail du produit anti-CD80 anticorps (APC)

N° du produit (Fournisseur): 200-326-n74

Fournisseur: Rockland

Fonction: CD80 Allophycocyanin Antibody

Réactivité croisée (Details): Reactivity is observed against human CD80.

Purification: Allophycocyanin conjugated CD80 Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against human CD80.

Stérilité: Sterile filtered

Immunogène: Anti-CD80 Antibody (Monoclonal) was produced by repeated immunizations with CD80 antigen.

Isotype: IgG1 kappa

Labeling Ratio: 1-2

Information d'application

Indications d'application:

Immunohistochemistry_Dilution: User Optimized

Flow_Cytometry_Dilution: 5 uL/test/1x10e5 to 1x10e8 cells

Western_Blot_Dilution: User Optimized

Commentaires:

Anti-CD80 is tested for Flow Cytometry and useful in Immunohistochemistry and Western Blot. Researchers should determine optimal titers for applications that are not stated.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 0.2 % BSA (w/v)

Preservative: 0.09 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store vial at 4° C prior to opening. Dilute only prior to immediate use. This product is stable at 4° C as an undiluted liquid. Use subdued lighting during handling and incubation of cells prior to analysis. Store reagent in the dark. DO NOT FREEZE.

Date de péremption: 6 months

Détails sur CD80

Antigène: CD80

Autre désignation: CD80

Sujet:

Synonyms: T-lymphocyte activation antigen CD80, Activation B7-1 antigen, BB1, CTLA-4 counter-receptor B7.1, B7, CD80, CD28LG, CD28LG1, LAB7

Background: CD80, also known as B7-1, B7, and BB1, is a 60 kD single chain type I glycoprotein belonging to the immunoglobulin superfamily. CD80 is expressed on activated B and T cells, macrophages, and dendritic cells. CD80 binds to CD28 and CD152 (CTLA-4). Along with CD86, CD80 plays a critical role in regulation of T cell activation. The interaction of CD80 with CD28 provides a potent costimulatory signal for T cell activation through the CD3 complex, while its interaction with CTLA-4 provides an inhibitory signal for T cell activation.

Gene Name: CD80

ID gène: 941

NCBI Accession: NP_005182

UniProt: P33681

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints