VEGFR2/CD309 anticorps (Extracellular Domain)

N° du produit ABIN6655552

N° du produit (Fournisseur): 200-301-p49

L’anticorps anti-VEGFR2/CD309 Monoclonal Souris est utilisé pour la détection de VEGFR2/CD309 dans des échantillons de Humain. Il a été validé pour IHC.

Aperçu rapide pour VEGFR2/CD309 anticorps (Extracellular Domain) (ABIN6655552)

Antigène: VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp VEGFR2/CD309 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: KDR-1

Détail du produit anti-VEGFR2/CD309 anticorps

Épitope: Extracellular Domain

N° du produit (Fournisseur): 200-301-p49

Fournisseur: Rockland

Fonction: VEGFR2 Antibody

Réactivité croisée (Details): This product reacts with human.

Purification: Anti-VEGFR2 antibody was purified from mouse ascites by protein A chromatography.

Immunogène: VEGFR2 antibody was produced in mice by repeated immunizations with recombinant protein corresponding to human extracellular domain of VEGFR-2 (KDR).

Isotype: IgG1

Information d'application

Indications d'application: Optional[Neutralization_Dilution]: 1:100-1:500

Commentaires:

Anti-VEGFR2 is tested for Immunohistochemistry-F. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~151.5 kDa corresponding to the appropriate cell lysate or extract.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution:

Reconstitution_Buffer: Neutral PBS

Reconstitution_Volume: 1.0 mL

Buffer:

Buffer: 1.2 % sodium acetate

Stabilizer: 2 mg BSA

Preservative: 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur VEGFR2/CD309

Antigène: VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

Autre désignation: VEGFR2

Sujet:

Synonyms: CD309, VEGFR, FLK1, VEGFR2, TYROSINE KINASE GROWTH FACTOR RECEPTOR, FLK1, MOUSE, HOMOLOG OF, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2, Fetal liver kinase 1, Kinase insert domain receptor, Protein-tyrosine kinase receptor flk-1

Background: VEGF, a homodimeric glycoprotein of relative molecular mass 45,000, is the only mitogen that specifically acts on endothelial cells. The importance of VEGF and its receptor system in tumor growth and intervention in this system may provide promising approaches to cancer therapy. VEGF receptor 2 is a member of a receptor tyrosine kinase family.Like other growth factor receptors, upon ligand binding VEGF receptor 2 dimerises and is autophosphorylated on multiple tyrosine residues. This antibody is suitable for researchers interested in cell signaling and cancer research.

Gene Name: KDR

ID gène: 3791

NCBI Accession: NP_002244

UniProt: P35968

Pathways: Signalisation RTK, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling