SETD7 anticorps

N° du produit ABIN6655577

Détail du produit anti-SETD7 anticorps

Antigène: SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SETD7 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée (Details): Cross reactivity with Set8 from species other than human not tested.

Purification: Anti-Set9 Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration.

Immunogène:

Immunogen: Anti-Set9 Antibody was produced in rabbits by repeated immunizations with a recombinant protein of human Set9.

Immunogen Type: Recombinant Protein

Information d'application

Indications d'application:

Application Note: Anti-Set9 Antibody is suitable for Western Blots. Specific conditions for reactivity should be optimized by the end user.  Expect a band approximately 50 kDa in the appropriate cell lysate or extract.

Western Blot Dilution: 1:1,000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

0.01 % (w/v) Sodium Azide

Stabilizer: None

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: RT,4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Détails sur SETD7

Antigène: SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))

Autre désignation: Set9 (SETD7 Produits)

Synonymes: anticorps KMT7, anticorps SET7, anticorps SET7/9, anticorps SET9, anticorps set7, anticorps zgc:101860, anticorps zgc:92330, anticorps 1600028F23Rik, anticorps H3K4MT, anticorps Set7, anticorps Set7/9, anticorps mKIAA1717, anticorps SET domain containing lysine methyltransferase 7, anticorps SET domain containing (lysine methyltransferase) 7, anticorps SETD7, anticorps setd7, anticorps Setd7

Sujet:

Synonyms: Histone-lysine N-methyltransferase SETD7, Histone H3-K4 methyltransferase SETD7, Lysine N-methyltransferase 7, SET domain-containing protein 7, SET 7/9, H3-K4-HMTase SETD7

Background: Set9 is a histone methyltransferase which specifically methylates lysine 4 of histone H3 being a specific tag for epigenetic transcriptional activation. Further, methylation of histone H3K4 by Set9 precludes deactylation of H3 by the NuRD complex and impairs Suv39h1-mediated methylation of H3K9. Set9 also methylates the tumor suppressor p53 at lysine 372, thereby enchancing its stability. IT contains a SET domain but lacks the pre- and post-SET domains. Anti-Set9 Antibody is ideal for research in Epigenetics, Gene Expression and Chromatin Remodeling.

Gene Name: SETD7

ID gène: 80854

NCBI Accession: NP_085151

UniProt: Q8WTS6