SNCA anticorps

N° du produit ABIN6656439

N° du produit (Fournisseur): 500-301-e56

Cet anticorps Souris Monoclonal détecte spécifiquement SNCA dans WB, ELISA, IF, FM et MA. Il présente une réactivité envers Humain.

Aperçu rapide pour SNCA anticorps (ABIN6656439)

Antigène: SNCA (Synuclein, alpha (SNCA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SNCA est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Fluorescence Microscopy (FM), Multiplex Assay (MA)

Clone: 2A7

Détail du produit anti-SNCA anticorps

N° du produit (Fournisseur): 500-301-e56

Fournisseur: Rockland

Fonction: Alpha Synuclein Antibody

Réactivité croisée (Details): Anti-Alpha Synuclein Antibody is directed against human Alpha Synuclein protein.

Purification: The antibody was purified by protein G purification from tissue culture supernatant.

Immunogène: Anti-Alpha Synuclein Antibody was produced by repeated immunizations with full length human alpha synuclein expressed in E. coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA_Dilution: 1:10,000

IF_Microscopy_Dilution: 1:500

Western_Blot_Dilution: 1:1000

Commentaires:

Alpha Synuclein antibody is tested for use in Western Blotting and IF. Specific conditions should be optimized by the end user. Expect a band of approximately 15 kDa in size corresponding to the alpha synuclein proteins in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Preservative: 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur SNCA

Antigène: SNCA (Synuclein, alpha (SNCA))

Autre désignation: Alpha Synuclein

Sujet:

Synonyms: mouse anti-Alpha Synuclein Antibody, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, NACP

Background: Alpha Synuclein Antibody detects Alpha Synuclein protein. Alpha-synuclein is a presynaptic neuronal protein that is thought to be involved in the formation of SNARE complexes. Most significantly, aggregated alpha-synuclein is one of the major components found in the Lewy bodies that occur in Parkinson's disease (PD) and other neurodegenerative disorders. Early onset Parkinson's disease may be caused by a duplication or triplication of one of the alpha synuclein genes. Alpha-synuclein is also found in the Lewy bodies of patients with diffuse Lewy body disease and inclusions in glial cells in the brains of patients with multiple system atrophy (MSA) and amyotrophic lateral sclerosis (ALS). Anti-Alpha-synuclein antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.

Gene Name: SNCA

ID gène: 6622

UniProt: P37840

Pathways: Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity