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Reticulon 4 anticorps

RTN4 Reactivité: Humain WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6656584
  • Antigène Voir toutes Reticulon 4 (RTN4) Anticorps
    Reticulon 4 (RTN4)
    Reactivité
    • 69
    • 49
    • 38
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 66
    • 3
    • 3
    • 2
    • 2
    Lapin
    Clonalité
    • 63
    • 13
    Polyclonal
    Conjugué
    • 36
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Cet anticorp Reticulon 4 est non-conjugé
    Application
    • 65
    • 28
    • 27
    • 21
    • 17
    • 17
    • 17
    • 9
    • 6
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
     Réactivité croisée
    Humain, Souris, Rat (Rattus)
    Purification
    Anti-Nogo A/B Antibody is sera. A BLAST analysis was used to suggest cross-reactivity with Anti-Nogo-A B from human, mouse, and rat based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-Nogo-A B from other sources has not been determined.
    Immunogène

    Immunogen: Nogo-A/B Antibody was produced from whole rabbit serum prepared by repeated immunizations with a synthetic sequence corresponding to internal Nogo-A human protein.

    Immunogen Type: Peptide

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    Discover our top product RTN4 Anticorps primaire
  • Indications d'application

    Immunohistochemistry Dilution: 1:100

    Application Note: Anti-Nogo A/B Antibody is suitable for use in IHC (p) and WB. Expect a band approximately 48-50 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

    Western Blot Dilution: 1:500-1:2000

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 0.05 % BSA

    0.05 % (w/v) Sodium Azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    RT,4 °C,-20 °C
    Stockage commentaire
    Store Nogo A B antibody at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
  • Antigène
    Reticulon 4 (RTN4)
    Autre désignation
    Nogo-A B (RTN4 Produits)
    Synonymes
    anticorps ASY, anticorps NI220/250, anticorps NOGO, anticorps NOGO-A, anticorps NOGOC, anticorps NSP, anticorps NSP-CL, anticorps Nbla00271, anticorps Nbla10545, anticorps Nogo-B, anticorps Nogo-C, anticorps RTN-X, anticorps RTN4-A, anticorps RTN4-B1, anticorps RTN4-B2, anticorps RTN4-C, anticorps RTN4-Cw, anticorps DKFZp459C0314, anticorps 1110020G17Rik, anticorps AA407876, anticorps AA409940, anticorps AA960376, anticorps C130026I10Rik, anticorps NgA, anticorps Nogo-A, anticorps mKIAA0886, anticorps mKIAA4153, anticorps NI-250, anticorps Nogo, anticorps Vp20, anticorps r, anticorps rat N, anticorps rat NogoA, anticorps reticulon-4, anticorps nogo, anticorps rtn4, anticorps wu:fb17a02, anticorps wu:fb22f12, anticorps wu:fd61a07, anticorps zgc:92163, anticorps reticulon 4, anticorps reticulon 4a, anticorps RTN4, anticorps rtn4, anticorps Rtn4, anticorps rtn4a
    Sujet

    Synonyms: KIAA0886, NOGO, Reticulon-4, Foocen, Neurite outgrowth inhibitor, Nogo protein, Neuroendocrine-specific protein, NSP, Neuroendocrine-specific protein C homolog, RTN-x, Reticulon-5

    Background: Nogo B 1/2 is a novel myelin-associated, intermediate-length splice variant of Nogo belonging to the reticulon family. It is a multi domain neurite growth inhibitory protein containing several discrete regions with growth inhibitory functions and is a component of the CNS myelin that prevents axonal regeneration in the adult vertebrate CNS. Nogo B1/2 along with NGBR mediated chemotaxis in HUVECs and induced tube formation in 3-dimensional cultures. It is mostly found in intact blood vessels, smooth muscle cells, and endothelial cell, with its N-terminus oriented extracellularly and is a regulator of vascular homeostasis and remodeling. It plays an important role in sporadic and familial amyotrophic lateral sclerosis. Anti-Nogo A/B is ideal for researchers interested in Neurobiology research.

    Gene Name: RTN4

    ID gène
    57142
    NCBI Accession
    NP_008939
    UniProt
    Q9NQC3
    Pathways
    Neurotrophin Signaling Pathway, Regulation of Cell Size, SARS-CoV-2 Protein Interactome
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