Reticulon 4 anticorps
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- Antigène Voir toutes Reticulon 4 (RTN4) Anticorps
- Reticulon 4 (RTN4)
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Reticulon 4 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Réactivité croisée
- Humain, Souris, Rat (Rattus)
- Purification
- Anti-Nogo A/B Antibody is sera. A BLAST analysis was used to suggest cross-reactivity with Anti-Nogo-A B from human, mouse, and rat based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-Nogo-A B from other sources has not been determined.
- Immunogène
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Immunogen: Nogo-A/B Antibody was produced from whole rabbit serum prepared by repeated immunizations with a synthetic sequence corresponding to internal Nogo-A human protein.
Immunogen Type: Peptide
- Top Product
- Discover our top product RTN4 Anticorps primaire
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- Indications d'application
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Immunohistochemistry Dilution: 1:100
Application Note: Anti-Nogo A/B Antibody is suitable for use in IHC (p) and WB. Expect a band approximately 48-50 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
Western Blot Dilution: 1:500-1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 0.05 % BSA
0.05 % (w/v) Sodium Azide - Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- RT,4 °C,-20 °C
- Stockage commentaire
- Store Nogo A B antibody at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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- Antigène
- Reticulon 4 (RTN4)
- Autre désignation
- Nogo-A B (RTN4 Produits)
- Synonymes
- anticorps ASY, anticorps NI220/250, anticorps NOGO, anticorps NOGO-A, anticorps NOGOC, anticorps NSP, anticorps NSP-CL, anticorps Nbla00271, anticorps Nbla10545, anticorps Nogo-B, anticorps Nogo-C, anticorps RTN-X, anticorps RTN4-A, anticorps RTN4-B1, anticorps RTN4-B2, anticorps RTN4-C, anticorps RTN4-Cw, anticorps DKFZp459C0314, anticorps 1110020G17Rik, anticorps AA407876, anticorps AA409940, anticorps AA960376, anticorps C130026I10Rik, anticorps NgA, anticorps Nogo-A, anticorps mKIAA0886, anticorps mKIAA4153, anticorps NI-250, anticorps Nogo, anticorps Vp20, anticorps r, anticorps rat N, anticorps rat NogoA, anticorps reticulon-4, anticorps nogo, anticorps rtn4, anticorps wu:fb17a02, anticorps wu:fb22f12, anticorps wu:fd61a07, anticorps zgc:92163, anticorps reticulon 4, anticorps reticulon 4a, anticorps RTN4, anticorps rtn4, anticorps Rtn4, anticorps rtn4a
- Sujet
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Synonyms: KIAA0886, NOGO, Reticulon-4, Foocen, Neurite outgrowth inhibitor, Nogo protein, Neuroendocrine-specific protein, NSP, Neuroendocrine-specific protein C homolog, RTN-x, Reticulon-5
Background: Nogo B 1/2 is a novel myelin-associated, intermediate-length splice variant of Nogo belonging to the reticulon family. It is a multi domain neurite growth inhibitory protein containing several discrete regions with growth inhibitory functions and is a component of the CNS myelin that prevents axonal regeneration in the adult vertebrate CNS. Nogo B1/2 along with NGBR mediated chemotaxis in HUVECs and induced tube formation in 3-dimensional cultures. It is mostly found in intact blood vessels, smooth muscle cells, and endothelial cell, with its N-terminus oriented extracellularly and is a regulator of vascular homeostasis and remodeling. It plays an important role in sporadic and familial amyotrophic lateral sclerosis. Anti-Nogo A/B is ideal for researchers interested in Neurobiology research.
Gene Name: RTN4
- ID gène
- 57142
- NCBI Accession
- NP_008939
- UniProt
- Q9NQC3
- Pathways
- Neurotrophin Signaling Pathway, Regulation of Cell Size, SARS-CoV-2 Protein Interactome
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