JUP anticorps

N° du produit ABIN6657477

N° du produit (Fournisseur): 200-301-p27

Cet anticorps Souris Monoclonal détecte spécifiquement JUP dans WB, IHC et ELISA. Il présente une réactivité envers Poulet.

Aperçu rapide pour JUP anticorps (ABIN6657477)

Antigène: JUP (Junction Plakoglobin (JUP))

Reactivité: Poulet

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp JUP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 15F11

Détail du produit anti-JUP anticorps

N° du produit (Fournisseur): 200-301-p27

Fournisseur: Rockland

Fonction: Catenin gamma (Plakoglobin) Antibody

Réactivité croisée (Details): This product reacts with human and bovine.

Purification: Anti-Catenin gamma (Plakoglobin) antibody was purified from mouse ascites by protein A chromatography.

Immunogène: Catenin gamma (Plakoglobin) antibody was produced in mice by repeated immunizations with a recombinant protein corresponding to chicken plakoglobin.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA_Dilution: 1:20,000

Immunohistochemistry_Dilution: 1:100-1:500

Western_Blot_Dilution: 1 μg/mL

Commentaires:

Anti-Catenin gamma is tested for Immunohistochemistry -F, immunocytochemistry, and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~81.8 kDa corresponding to the appropriate cell lysate or extract.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution:

Reconstitution_Buffer: Neutral PBS

Reconstitution_Volume: 1.0 mL

Buffer:

Buffer: 1.2 % sodium acetate

Stabilizer: 2 mg BSA

Preservative: 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur JUP

Antigène: JUP (Junction Plakoglobin (JUP))

Autre désignation: Catenin gamma (Plakoglobin)

Sujet:

Synonyms: DP3, PDGB, PKGB, CTNNG, DPIII, ARVD12, Catenin gamma, Desmoplakin III, Desmoplakin-3

Background: Junction Plakoglobin (JUP) ,also knows as catenin gamma, is a major cytoplasmic protein that occurs in a soluble and a membrane-associated form and is the only known constituent common to the submembranous plaques of both kinds of adhering junctions, the desmosomes and the intermediate junctions. It is a component of the cadherin-catenin complex, which is predominantly localized where actin filaments anchor in adherens junctions of epithelial cells. The human plakoglobin gene localizes on chromosome 17q21. Gamma-catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of beta-catenin. This antibody is suitable for researchers interested in cell adhesion and cancer research.

Gene Name: JUP

ID gène: 3728

NCBI Accession: NP_002221

UniProt: P14923

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location