ITGA3 anticorps (N-Term)

N° du produit ABIN6657511

N° du produit (Fournisseur): 600-401-r13

L’anticorps Lapin Polyclonal anti-ITGA3 a été validé pour WB, FACS, IHC et FM. Il convient pour détecter ITGA3 dans des échantillons de Humain.

Aperçu rapide pour ITGA3 anticorps (N-Term) (ABIN6657511)

Antigène: ITGA3 (Integrin, alpha 3 (ITGA3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ITGA3 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Fluorescence Microscopy (FM)

Détail du produit anti-ITGA3 anticorps

Épitope: N-Term

N° du produit (Fournisseur): 600-401-r13

Fournisseur: Rockland

Fonction: ITGA3 Antibody

Réactivité croisée (Details): Anti-ITGA3 antibody is directed against human ITGA3 protein.

Purification: The product was affinity purified from monospecific antiserum by immunoaffinity purification.

Immunogène: ITGA3 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a sequence at the N-terminal of human ITGA3.

Isotype: IgG

Information d'application

Indications d'application:

Immunohistochemistry_Dilution: 2-5 μg/mL

Flow_Cytometry_Dilution: 1-3 μg/1x10^6 cells

IF_Microscopy_Dilution: 5 μg/mL

Western_Blot_Dilution: 0.1-0.5 μg/mL

Commentaires:

Anti-ITGA3 is tested for Immunohistochemistry -P, ICC/IF, Flow Cytometry, and Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~116.6 kDa corresponding to the appropriate cell lysate or extract. 0.05 mg sodium azide and 0.05 mg Thimerosal have been added as preservatives.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution:

Reconstitution_Buffer: Restore with deionized water (or equivalent)

Reconstitution_Volume: 100 μL

Buffer:

Buffer: 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide

Stabilizer: 5 mg BSA

Preservative: 0.05 mg Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur ITGA3

Antigène: ITGA3 (Integrin, alpha 3 (ITGA3))

Autre désignation: ITGA3

Sujet:

Synonyms: CD49 antigen-like family member C,FRP-2,Galactoprotein B3,

Background: ITGA3(INTEGRIN, ALPHA-3), also called CD49C, VLA3 or GAPB3, is a protein that in humans is encoded by the ITGA3 gene. ITGA3 is an integrin alpha subunit which is also a member of the family of cell surface adhesion molecules. ITGA3 is mapped to chromosome 17 and its exact cytogenetic location is 17q21.33. ITGA3 makes up half of the alpha3beta1 integrin duplex that plays a role in neural migration and corticogenesis together with beta-1 subunit.A functional link between DAB1 phosphorylation and ITGA3 signaling drives the timely detachment of migrating neurons from radial glial fibers. Expression of human ITGA3 increased the infectivity of virus for Chinese hamster ovary cells. ITGA3 also contains 13 potential N-glycosylation sites, 2 potential cleavage sites, and the 7 N-terminal repeating units characteristic of ITGAs. Recombinant ITGA3 is expressed as a 150-kD protein as the same size as the native protein by the western blot analysis. This antibody is suitable for researchers interested in cancer research.

Gene Name: ITGA3

ID gène: 3675

NCBI Accession: NP_002195

UniProt: P26006

Pathways: CXCR4-mediated Signaling Events, Integrin Complex