MAP2K5 anticorps (pSer311, pThr315)

N° du produit ABIN6658265

N° du produit (Fournisseur): 612-401-d74

Cet anticorps anti-MAP2K5 est un anticorps Lapin Polyclonal détectant MAP2K5 dans WB. Adapté pour Rat.

Aperçu rapide pour MAP2K5 anticorps (pSer311, pThr315) (ABIN6658265)

Antigène: MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP2K5 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MAP2K5 anticorps

Épitope: pSer311, pThr315

N° du produit (Fournisseur): 612-401-d74

Fournisseur: Rockland

Fonction: MEK5 phospho S311/phospho T315 Antibody

Réactivité croisée (Details): MEK5 antibody was affinity purified from monospecific antiserum by immunoaffinity purification.

Purification: Anti-MEK5 pS311/pT315 antibody is directed against rat MEK5.

Immunogène: Anti-MEK5 pS311/pT315 Antibody was produced in rabbit by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser311/Thr315 conjugated to KLH.

Isotype: IgG

Information d'application

Indications d'application: Optional[Neutralization_Dilution]: 1:1000

Commentaires:

Anti-MEK5 pS311/pT315 (Rabbit) antibody is tested for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 49 kDa in size corresponding to MEK5 protein phosphorylated at Ser311/Thr315 in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur MAP2K5

Antigène: MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))

Autre désignation: MEK5

Sujet:

Synonyms: Dual specificity mitogen-activated protein kinase kinase 5, MAP kinase kinase 5, MAPKK 5, MAPK/ERK kinase 5

Background: MEK5 pS311/pT315 antibody detects MEK5 that is phosphorylated at Ser311 and Threonine315. MEK5 (also known as MKK5) is a dual specificity serine/threonine protein kinase belonging to the MAP kinase kinase family. MEK5 has been shown to specifically activate ERK5 whereas MEK5 itself is regulated by MEKK3. An important link between MEK5 and metastatic prostrate cancer has been demonstrated. Dual phosphorylation of Ser311 and Thr315 have been implicated in cell proliferation. Therefore, MEK5 pS311/pT315 antibody is ideal for investigators involved in Cell Signaling, Cell Migration and Proliferation and, more generally in Cancer Research.

Gene Name: MAP2K5

ID gène: 29568

UniProt: Q62862

Pathways: Signalisation MAPK, Neurotrophin Signaling Pathway