Angiotensin I Converting Enzyme 1 anticorps (PE-Cy5)

N° du produit ABIN668643

Cet anticorps anti-Angiotensin I Converting Enzyme 1 est un anticorps Polyclonal produit chez le Lapin, détectant Angiotensin I Converting Enzyme 1 dans WB et FACS. Convient pour Humain, Souris, Rat, Porc, Chien et Boeuf (Vache).

Aperçu rapide pour Angiotensin I Converting Enzyme 1 anticorps (PE-Cy5) (ABIN668643)

Antigène: Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))

Reactivité: Humain, Souris, Rat, Porc, Chien, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Angiotensin I Converting Enzyme 1 est conjugé à/à la PE-Cy5

Application: Western Blotting (WB), Flow Cytometry (FACS)

Détail du produit anti-Angiotensin I Converting Enzyme 1 anticorps (PE-Cy5)

Réactivité croisée: Chien, Humain, Souris, Rat

Homologie: Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from Human ACE1

Isotype: IgG

Information d'application

Indications d'application: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Angiotensin I Converting Enzyme 1

Antigène: Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))

Autre désignation: ACE

Sujet:

Synonyms: Angiotensin Converting Enzyme 1, ACE, ACE-T, Dipeptidyl carboxy peptidase 1, Kininase II, ACE-1, testis-specic isoform precursor, ACE1, Angiotensin converting enzyme testis specic isoform, Carboxycathepsin, CD 143, DCP 1, Dipeptidyl carboxypeptidase 1, MVCD3, Peptidase P, Peptidyl dipeptidase A, Testicular ECA

Background: Angiotensin Converting enzyme is involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. ACE converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilatator. ACE exists in two forms, a 170KD somatic form and a 90KD germinal form. The somatic form is expressed by endothelial cells (especially those of lung capillaries and arterioles), epithelial cells (especially in proximal renal tubules and small intestine), by some neuronal cells and variably by some macrophages and T lymphocytes. The germinal form is expressed by spermatozoa.

Poids moléculaire: 181kDa

ID gène: 1636

UniProt: P12821

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration