Angiopoietin 2 anticorps (AA 401-496) (Cy3)

N° du produit ABIN671784

Cet anticorps anti-Angiopoietin 2 est un anticorps Lapin Polyclonal détectant Angiopoietin 2 dans WB, IF (cc) et IF (p). Adapté pour Humain.

Aperçu rapide pour Angiopoietin 2 anticorps (AA 401-496) (Cy3) (ABIN671784)

Antigène: Angiopoietin 2 (ANGPT2)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Angiopoietin 2 est conjugé à/à la Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-Angiopoietin 2 anticorps (Cy3)

Épitope: AA 401-496

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Pig,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Angiopoietin 2

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Angiopoietin 2

Antigène: Angiopoietin 2 (ANGPT2)

Autre désignation: Angiopoietin 2

Sujet:

Synonyms: ANG2, AGPT2, Angiopoietin-2, ANG-2, ANGPT2

Background: Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.

ID gène: 285

UniProt: O15123

Pathways: Signalisation RTK