SPHK2 anticorps (AA 215-269) (DyLight 550)

N° du produit ABIN7354616

Cet anticorps Lapin Polyclonal détecte spécifiquement SPHK2 dans FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour SPHK2 anticorps (AA 215-269) (DyLight 550) (ABIN7354616)

Antigène: SPHK2 (Sphingosine Kinase 2 (SPHK2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPHK2 est conjugé à/à la DyLight 550

Application: Flow Cytometry (FACS)

Détail du produit anti-SPHK2 anticorps (DyLight 550)

Épitope: AA 215-269

Fonction: Anti-Human SPHK2 DyLight® 550 conjugated Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-Human SPHK2 DyLight® 550 conjugated Antibody -Dyl550. Tested in Flow Cytometry applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human SPHK2 recombinant protein (Position: F215-M269).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells1. Hait NC, Sarkar S, Le Stunff H, Mikami A, Maceyka M, Milstien S, Spiegel S (August 2005). "Role of sphingosine kinase 2 in cell migration toward epidermal growth factor". The Journal of Biological Chemistry. 280 (33): 29462-9. 2. Liu H, Sugiura M, Nava VE, Edsall LC, Kono K, Poulton S, Milstien S, Kohama T, Spiegel S (June 2000). "Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform". The Journal of Biological Chemistry. 275 (26): 19513-20.

Commentaires:

Other applications have not been tested. Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Détails sur SPHK2

Antigène: SPHK2 (Sphingosine Kinase 2 (SPHK2))

Autre désignation: SPHK2

Sujet:

Synonyms: Sphingosine kinase 2, SK 2, SPK 2

Background: Sphingosine kinase 2 is a protein that in humans is encoded by the SPHK2 gene. This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Poids moléculaire: 39 kDa

ID gène: 56848

Pathways: VEGF Signaling