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CD2AP anticorps (AA 253-337)

Cd2ap Reactivité: Humain, Rat, Souris WB, IHC (p), FACS Hôte: Souris Monoclonal 5F8 unconjugated
N° du produit ABIN6719544
  • Antigène Voir toutes CD2AP (Cd2ap) Anticorps
    CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))
    Épitope
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 253-337
    Reactivité
    Humain, Rat, Souris
    Hôte
    • 23
    • 1
    • 1
    Souris
    Clonalité
    • 24
    • 1
    Monoclonal
    Conjugué
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD2AP est non-conjugé
    Application
    • 13
    • 10
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Fonction
    Mouse IgG monoclonal antibody for CD2AP detection. Tested with WB, IHC-P, FCM in Human,Mouse,Rat.
    Réactivité croisée (Details)
    No cross reactivity with other proteins.
    Attributs du produit
    Mouse IgG monoclonal antibody for CD2AP detection. Tested with WB, IHC-P, FCM in Human,Mouse,Rat.
    Purification
    Immunogen affinity purified.
    Immunogène
    E. coli-derived human CD2AP recombinant protein (Position: K253-K337).
    Clone
    5F8
    Isotype
    IgG
    Top Product
    Discover our top product Cd2ap Anticorps primaire
  • Indications d'application

    Application details: Western blot|0.1-0.5 μg/mL Immunohistochemistry(Paraffin-embedded Section)|0.5-1 μg/mL Flow Cytometry|1-3 μg/1x106 cells

    Commentaires

    Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Buffer
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Antigène
    CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))
    Autre désignation
    CD2AP (Cd2ap Produits)
    Synonymes
    anticorps cd2apl, anticorps fj51c01, anticorps im:7153970, anticorps si:ch211-207n9.1, anticorps wu:fj51c01, anticorps zgc:103705, anticorps DKFZp469E061, anticorps CMS, anticorps AL024079, anticorps C78928, anticorps METS-1, anticorps Mets1, anticorps CD2-associated protein L homeolog, anticorps CD2 associated protein, anticorps CD2-associated protein, anticorps cd2ap.L, anticorps CD2AP, anticorps cd2ap, anticorps Cd2ap
    Sujet

    Synonyms: CD2-associated protein, Adapter protein CMS, Cas ligand with multiple SH3 domains, CD2AP

    Background: CD2-associated protein is a protein that in humans is encoded by the CD2AP gene. This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.

    ID gène
    23607
    UniProt
    Q9Y5K6
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