CD3 anticorps (mFluor™450)

N° du produit ABIN6731073

Cet anticorps anti-CD3 est un anticorps Souris Monoclonal détectant CD3 dans FACS. Adapté pour Humain.

Aperçu rapide pour CD3 anticorps (mFluor™450) (ABIN6731073)

Antigène: CD3

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD3 est conjugé à/à la mFluor™450

Application: Flow Cytometry (FACS)

Classe de qualité: GMP Grade

Clone: UCHT1

Détail du produit anti-CD3 anticorps (mFluor™450)

Fonction: CD3 mFluor™ 450 Antibody

Attributs du produit: The monoclonal UCHT1 clone recognizes CD3ε antigen, a 20KDa transmembrane cell-surface protein that belongs to the immunoglobulin superfamily. The CD3 complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains. These chains associate with a molecule known as the T-cell receptor (TCR) and the ζ-chain (zeta-chain) to generate an activation signal in T lymphocytes. CD3ε is expressed on T lymphocytes, NK-T cells, and to varying degrees on developing thymocytes. CD3 plays central roles in TCR signaling, T lymphocyte activation, and antigen recognition. Crosslinking of the TCR via plate bound UCHT1 monoclonal is widely used to study the activation T cell response in vitro.

Purification: Purified

Pureté: >95 %

Immunogène: Thymocytes and peripheral blood lymphocytes from a Sézary Syndrome donor

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: 2-8°C, Conjugated antibodies should never be frozen.

Détails sur CD3

Antigène: CD3

Autre désignation: CD3

ID gène: 916

NCBI Accession: NM_000733

UniProt: P07766

Pathways: TCR Signaling, Ubiquitin Proteasome Pathway