CD3 anticorps (mFluor™450)
Aperçu rapide pour CD3 anticorps (mFluor™450) (ABIN6731073)
Antigène
Voir toutes CD3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
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Fonction
- CD3 mFluor™ 450 Antibody
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Attributs du produit
- The monoclonal UCHT1 clone recognizes CD3ε antigen, a 20KDa transmembrane cell-surface protein that belongs to the immunoglobulin superfamily. The CD3 complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains. These chains associate with a molecule known as the T-cell receptor (TCR) and the ζ-chain (zeta-chain) to generate an activation signal in T lymphocytes. CD3ε is expressed on T lymphocytes, NK-T cells, and to varying degrees on developing thymocytes. CD3 plays central roles in TCR signaling, T lymphocyte activation, and antigen recognition. Crosslinking of the TCR via plate bound UCHT1 monoclonal is widely used to study the activation T cell response in vitro.
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Purification
- Purified
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Pureté
- >95 %
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Immunogène
- Thymocytes and peripheral blood lymphocytes from a Sézary Syndrome donor
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Isotype
- IgG1, kappa
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anti-CD3 (CD3) antibody
CD3 Reactivité: Humain, Souris, Rat IHC, IF, WB Hôte: Lapin Polyclonal unconjugated
anti-CD3 (CD3) antibodyCD3 Reactivité: Humain, Non-Human Primate FACS, IP, IHC (fro), ICC, MS Hôte: Souris Monoclonal UCHT1 unconjugated
anti-CD3 (CD3) antibodyCD3 Reactivité: Humain FACS, IP, MS Hôte: Souris Monoclonal MEM-57 unconjugated
anti-CD3 (CD3) antibodyCD3 Reactivité: Humain, Non-Human Primate FACS, IP, IHC (fro), Func, MS Hôte: Souris Monoclonal UCHT1 unconjugated
anti-CD3 (CD3) antibodyCD3 Reactivité: Humain FACS, IP, Func, MS Hôte: Souris Monoclonal MEM-57 unconjugated
anti-CD3 (CD3) antibody (Biotin)CD3 Reactivité: Humain FACS, IP Hôte: Souris Monoclonal MEM-57 Biotin
anti-CD3 (CD3) antibody (Biotin)CD3 Reactivité: Humain, Non-Human Primate FACS, IP, IHC (fro) Hôte: Souris Monoclonal UCHT1 Biotin
anti-CD3 (CD3) antibody (APC)CD3 Reactivité: Humain FACS Hôte: Souris Monoclonal MEM-57 APC
anti-CD3 (CD3) antibody (PE)CD3 Reactivité: Humain FACS Hôte: Souris Monoclonal MEM-57 PE
anti-CD3 (CD3) antibody (PerCP)CD3 Reactivité: Humain, Non-Human Primate FACS Hôte: Souris Monoclonal UCHT1 PerCP
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- 2-8°C, Conjugated antibodies should never be frozen.
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- CD3
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Autre désignation
- CD3
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ID gène
- 916
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NCBI Accession
- NM_000733
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UniProt
- P07766
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Pathways
- TCR Signaling, Ubiquitin Proteasome Pathway
Antigène
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