CD59 anticorps (FITC)
Aperçu rapide pour CD59 anticorps (FITC) (ABIN6735023)
Antigène
Voir toutes CD59 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- Binds to a 17-25kD glycoprotein, which is distributed on human cells and has a glycosyl-phosphatidylinositol (GPI) linkage to the plasma membrane. Cell reactivity: Recognizes all leucocytes, platelets, fibroblasts, erythrocytes and most cell lines. It is negative on U937 and Daudi cell lines. It is reduced on affected cells from patients with PNH with a distribution reflecting the clonal nature of the disease.
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Purification
- Purified
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Immunogène
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Human erythrocytes.
Type of Immunogen: Cells -
Isotype
- IgG1
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Indications d'application
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Approved: Flo, IF (1:25)
Usage: Studies of complement and homologous restriction of complement action of the properties of GPI linked proteins and in the characterization of cells from patients with PNH. Flow cytometry and indirect immunofluorescence: 1:25. Dilute with isotonic buffer. Use 50 μL of the appropriate dilution per 1x1 x106 in 100 μL buffer. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. -
Commentaires
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, pH 7.4, 0.2 % BSA, 0.1 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.
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- CD59
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Autre désignation
- CD59
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Sujet
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Name/Gene ID: CD59
Synonyms: CD59, 16.3A5, 1F5, 1F5 antigen, CD59 glycoprotein, EL32, EJ16, G344, HRF-20, MAC-IP, MACIF, Ly-6-like protein, MEM43, MIRL, MEM43 antigen, MIN2, MIN3, MSK21, p18-20, Protectin, MAC-inhibitory protein, MIC11, T cell-activating protein, CD59 antigen, EJ30, HRF20, Human leukocyte antigen MIC11, Lymphocytic antigen CD59/MEM43, MIN1 -
ID gène
- 966
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UniProt
- P13987
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Pathways
- Système du Complément
Antigène
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