Fibrinogen anticorps (FITC)

N° du produit ABIN673861

Cet anticorps Lapin Polyclonal détecte spécifiquement Fibrinogen dans IF (p) et IF (cc). Il présente une réactivité envers Humain et Rat et a été mentionné dans 2+ publications.

Aperçu rapide pour Fibrinogen anticorps (FITC) (ABIN673861)

Antigène: Fibrinogen

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Fibrinogen est conjugé à/à la FITC

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Détail du produit anti-Fibrinogen anticorps (FITC)

Réactivité croisée: Humain, Rat

Homologie: Mouse

Purification: Purified by Protein A.

Immunogène: Fibrinogen from human plasma

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-Fibrinogen (FITC) (ABIN673861)

Chen, Yang, Liao, Wang, Chen, Sun, Huang: "Effect of the duration of UV irradiation on the anticoagulant properties of titanium dioxide films." dans: ACS applied materials & interfaces, Vol. 7, Issue 7, pp. 4423-32, (2015) (PubMed).

Chen, Zhao, Chen, Liao, Yang, Sun, Huang: "The effect of full/partial UV-irradiation of TiO2 films on altering the behavior of fibrinogen and platelets." dans: Colloids and surfaces. B, Biointerfaces, Vol. 122, pp. 709-18, (2014) (PubMed).

Détails sur Fibrinogen

Antigène: Fibrinogen

Sujet:

Synonyms: Fib2, Fibrinogen alpha chain, FGA

Background: Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the immune response via both innate and T-cell mediated pathways.

ID gène: 2243

UniProt: P02671