PDE4D anticorps (AA 401-550)

N° du produit ABIN674964

Détail du produit anti-PDE4D anticorps

Antigène: PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))

Épitope: AA 401-550

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE4D est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PDE4D

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur PDE4D

Antigène: PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))

Autre désignation: PDE4D (PDE4D Produits)

Synonymes: anticorps ACRDYS2, anticorps DPDE3, anticorps HSPDE4D, anticorps PDE43, anticorps PDE4DN2, anticorps STRK1, anticorps CMYA2, anticorps MMGL, anticorps 9630011N22Rik, anticorps Dpde3, anticorps 4732458A06Rik, anticorps 9430063L05Rik, anticorps C87016, anticorps D130016K21Rik, anticorps D3Bwg1078e, anticorps Usmg4, anticorps mKIAA0454, anticorps si:dkey-190g11.2, anticorps phosphodiesterase 4D, anticorps phosphodiesterase 4D interacting protein, anticorps phosphodiesterase 4D, cAMP specific, anticorps phosphodiesterase 4D, cAMP-specific, anticorps phosphodiesterase 4D interacting protein (myomegalin), anticorps PDE4D, anticorps PDE4DIP, anticorps pde4d, anticorps Pde4dip, anticorps Pde4d

Sujet:

Synonyms: cAMP specic 3',5' cyclic phosphodiesterase 4D, DKFZp686M11213, FLJ97311, cAMP specic 3' 5' cyclic phosphodiesterase 4D, cAMP specic phosphodiesterase 4D, cAMP specic phosphodiesterase PDE4D, cAMP specic phosphodiesterase PDE4D6, cyclic AMP phosphodiesterase, DPDE 3, DPDE3, Dunce like phosphodiesterase E3, HSPDE4D, PDE 43, PDE43, PDE4DN2, Phosphodiesterase 4D cAMP specic dunce Drosophila homolog phosphodiesterase E3, Phosphodiesterase 4D cAMP specic phosphodiesterase E3 dunce homolog Drosophila, Phosphodiesterase 4D cAMP specic, Phosphodiesterase 4D, cAMP specic dunce, Phosphodiesterase E3 dunce homolog Drosophila, STRK 1, STRK1.

Background: Cyclic AMP-dependent phosphodiesterase type D (PDE4D) family is comprise of 5 variants (PDE4D1, D2, D3, D4 and D5). One or more PDE4D subtype variants are ubiquitously present in all mammalian cells. In CNS all five PDE4D subtype variants are expressed in varying ratios and their activity is regulated in tandem with GPCRs stimulation. Peripheral tissues also exhibit differential expression of PDE4D variants. PDE4D1/D2 mRNA levels rise in response to an increase in cAMP. Short term regulation of PDE4D variants involved PKA, MAP kinases and Erk2 phosphorylation that results in rapid change in their enzymatic activities. Other regulatory mechanism involved protein protein interactions with cytoskeletal scaffolding proteins.

ID gène: 5144

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling