S100B anticorps (AA 31-92) (Cy3)

N° du produit ABIN676706

Détail du produit anti-S100B anticorps (Cy3)

Antigène: S100B (S100 Calcium Binding Protein B (S100B))

Épitope: AA 31-92

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp S100B est conjugé à/à la Cy3

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Réactivité croisée: Rat

Homologie: Human,Mouse,Cow,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human S100B

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur S100B

Antigène: S100B (S100 Calcium Binding Protein B (S100B))

Autre désignation: S100b (S100B Produits)

Synonymes: anticorps NEF, anticorps S100, anticorps S100-B, anticorps S100beta, anticorps S100P, anticorps AI850290, anticorps Bpb, anticorps si:dkey-110p14.2, anticorps wu:fq18b10, anticorps zgc:92776, anticorps S100 calcium binding protein B, anticorps S100 protein, beta polypeptide, neural, anticorps S100 calcium binding protein, beta (neural), anticorps S100B, anticorps S100b, anticorps s100b

Sujet:

Synonyms: NEF, S1, S1-B, S1beta, Protein S1-B, S-1 protein beta chain, S-1 protein subunit beta, S1 calcium-binding protein B, S1B

Background: Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.

ID gène: 6285

UniProt: P04271

Pathways: Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins