IL-6 Receptor anticorps

N° du produit ABIN6774202

Détail du produit anti-IL-6 Receptor anticorps

Antigène: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-6 Receptor est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Neutralization (Neut)

Specificité: Recognizes human IL-6R.

Purification: Protein G purified

Immunogène: Sf 21-derived rhIL-6R.

Type of Immunogen: Recombinant protein

Clone: 17506

Isotype: IgG1

Information d'application

Indications d'application: Approved: ELISA, Flo (25 μg/mL), Neut, WB (1 - 2 μg/mL)

Usage: Suitable for use in Neutralization, Western Blot, ELISA and Flow Cytometry. Neutralization of Human IL6 R Bioactivity: ~0.1-0.2 μg/mL in the presence of 20 ng/mL of rhIL-6 R and 20 ng/mL of rhIL-6, using the M1 cell line. Western Blot: 1-2 μg/mL, The detection limit is ~100 ng/lane under non-reducing and reducing conditions. ELISA Capture: 2-8 μg/mL. Use biotinylated human IL-6 R detection antibody and recombinant human IL-6 R as the standard. Flow Cytometry: 25 μg/mL, 10 μL labels 1-2.5x10^5 U937 cells in a total reaction volume <200 μL.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Sterile PBS

Concentration: Lot specific

Buffer: Lyophilized, PBS, 5 % trehalose

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Détails sur IL-6 Receptor

Antigène: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Autre désignation: IL6R / IL6 Receptor (IL6R Produits)

Synonymes: anticorps IL6R, anticorps il-6ra, anticorps CD126, anticorps IL-6R-1, anticorps IL-6RA, anticorps IL6Q, anticorps IL6RA, anticorps IL6RQ, anticorps gp80, anticorps IL6R1, anticorps Il6ra, anticorps IL-6Ralpha, anticorps IL-6R, anticorps Il6r, anticorps interleukin 6 receptor, anticorps interleukin 6 receptor, alpha, anticorps IL6R, anticorps il6r, anticorps Il6r, anticorps Il6ra

Sujet: Name/Gene ID: IL6R
Family: Interleukin

Synonyms: IL6R, CD126, gp80, IL-6R subunit alpha, IL-6R-alpha, IL-6RA, IL6Q, IL-6 receptor subunit alpha, IL-6R 1, IL-6R-1, Interleukin 6 receptor, Membrane glycoprotein 80, CD126 antigen, IL6RA, IL6RQ

ID gène: 3570

UniProt: P08887

Pathways: Signalistation JAK/STAT, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints