DKK1 anticorps (AA 201-266) (HRP)

N° du produit ABIN678167

Détail du produit anti-DKK1 anticorps (HRP)

Antigène: DKK1 (Dickkopf Homolog 1 (DKK1))

Épitope: AA 201-266

Reactivité: Humain, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DKK1 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Chien, Humain

Homologie: Mouse,Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human DKK1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-DKK1 (HRP) (ABIN678167)

Pontremoli, Brioschi, Baetta, Ghilardi, Banfi: "Identification of DKK-1 as a novel mediator of statin effects in human endothelial cells." dans: Scientific reports, Vol. 8, Issue 1, pp. 16671, (2018) (PubMed).

Détails sur DKK1

Antigène: DKK1 (Dickkopf Homolog 1 (DKK1))

Autre désignation: DKK1 (DKK1 Produits)

Synonymes: anticorps DKK-1, anticorps SK, anticorps AI414495, anticorps SGY, anticorps SGY-1, anticorps SGY1, anticorps Soggy, anticorps mSgy, anticorps dkk1, anticorps dkk, anticorps dkk-1, anticorps xdkk1, anticorps Xdkk-1, anticorps Dickkopf1, anticorps dickkopf-1, anticorps mdkk-1, anticorps dkk1-A, anticorps dickkopf WNT signaling pathway inhibitor 1, anticorps dickkopf like acrosomal protein 1, anticorps dickkopf-related protein 1, anticorps dickkopf-like 1, anticorps dickkopf WNT signaling pathway inhibitor 1b, anticorps dickkopf protein, anticorps dickkopf WNT signaling pathway inhibitor 1 S homeolog, anticorps DKK1, anticorps Dkk1, anticorps DKKL1, anticorps LOC100228789, anticorps Dkkl1, anticorps dkk1b, anticorps dkk1, anticorps dickkopf, anticorps dkk1.S

Sujet:

Synonyms: SK, DKK-1, Dickkopf-related protein 1, Dickkopf-1, hDkk-1, DKK1, UNQ492/PRO18

Background: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.

ID gène: 22943

UniProt: O94907

Pathways: Signalisation WNT, Regulation of Muscle Cell Differentiation, Positive Regulation of fat Cell Differentiation