NOTCH2 anticorps (AA 1501-1700)

N° du produit ABIN680183

L’anticorps Lapin Polyclonal anti-NOTCH2 a été validé pour WB, ELISA, IF (cc), IF (p), IHC (p) et IHC (fro). Il convient pour détecter NOTCH2 dans des échantillons de Humain et Souris.

Aperçu rapide pour NOTCH2 anticorps (AA 1501-1700) (ABIN680183)

Antigène: NOTCH2 (Notch 2 (NOTCH2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NOTCH2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-NOTCH2 anticorps

Épitope: AA 1501-1700

Réactivité croisée: Humain, Souris

Homologie: Rat,Pig,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Notch2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur NOTCH2

Antigène: NOTCH2 (Notch 2 (NOTCH2))

Autre désignation: Notch 2

Sujet:

Synonyms: hN2, AGS2, HJCYS, Neurogenic locus notch homolog protein 2, Notch 2, NOTCH2

Background: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs (By similarity). Involved in bone remodeling and homeostasis. In collaboration with RELA/p65 enhances NFATc1 promoter activity and positively regulates RANKL-induced osteoclast differentiation.

ID gène: 4853

UniProt: Q04721

Pathways: Signalisation Notch, Stem Cell Maintenance