CD44 anticorps (Exon v10) (PE-Cy5)

N° du produit ABIN680605

Cet anticorps Lapin Polyclonal détecte spécifiquement CD44 dans IF (p). Il présente une réactivité envers Humain, Souris, Rat, Chien et Porc.

Aperçu rapide pour CD44 anticorps (Exon v10) (PE-Cy5) (ABIN680605)

Antigène: CD44

Reactivité: Humain, Souris, Rat, Chien, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD44 est conjugé à/à la PE-Cy5

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-CD44 anticorps (PE-Cy5)

Épitope: Exon v10

Specificité: Excitation / Emission Wavelengths: 480,565,650nm/670nm

Purification: Antibodies are purified by protein A and peptide affinity chromatography.

Immunogène: Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from human CD44v10
Please inquire for sequence information.

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1mg/1ml

Buffer: 0.01M PBS, pH 7.4 with 10 mg/ml BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur CD44

Antigène: CD44

Autre désignation: CD44

Sujet: CD44 is a receptor for hyaluronic acid (HA). It mediates cell-cell and cell-matrix interactions through its affinity for HA and possibly also through its affinity for other ligands such as osteopontin collagens and matrix matalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration tumor growth and progression. Also involved in lymphocyte activation recirculation and homing and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.
Synonym: ECMR III, Epican, Heparan sulfate proteoglycan, HUTCH I, Hyaluronate receptor, PGP 1, CD44 antigen, CD44 molecule, CDw44, ECMR III, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, Heparan sulfate proteoglycan, Hermes antigen, HUTCH I, Hyaluronate receptor, PGP 1, Phagocytic glycoprotein I.

Poids moléculaire: 82kDa

ID gène: 960

Pathways: Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling