CEACAM1/5 anticorps (CF®488A)

N° du produit ABIN6933700

Détail du produit anti-CEACAM1/5 anticorps (CF®488A)

Antigène: CEACAM1/5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1/5 (CEACAM1/5))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CEACAM1/5 est conjugé à/à la CF®488A

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Test (T)

Specificité: This antibody recognizes proteins of 80-200 kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70 % are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.

Réactivité croisée (Details): Human,

Purification: Antibody Purified from Bioreactor Concentrate by Protein A/G and conjugated to various reporter molecules.

Immunogène: Recombinant full-length human CEA protein

Clone: C66-1009

Isotype: IgG2a

Information d'application

Indications d'application:

Positive Control: MCF7 or 293T cells. Colon carcinoma.

Known Application: Flow Cytometry (5 µL per test per one million cells or 5 µL per 100 µL of whole blood),Immunofluorescence (1:50-1:100),Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 100 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.

Date de péremption: 24 months

Détails sur CEACAM1/5

Antigène: CEACAM1/5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1/5 (CEACAM1/5))

Autre désignation: CEACAM1 & CEACAM5 (CEACAM1/5 Produits)

Synonymes: anticorps CD66e, anticorps CEA, anticorps carcinoembryonic antigen related cell adhesion molecule 5, anticorps CEACAM5

Sujet: Carcinoembryonic Antigen-related Cell Adhesion Molecule 5, CEACAM5, CD66, Biliary Glycoprotein (BGP-1),Carcinoembryonic Antigen (CEA) / CD66
Cellular localisation: Cytoplasmic and luminal surface

Poids moléculaire: 80-200kDa

ID gène: 1048, 634, 709196

UniProt: P06731