PD-L1 anticorps (AA 39-191) (PE)

N° du produit ABIN6935090

Cet anticorps Souris Monoclonal détecte spécifiquement PD-L1 dans FACS et IF. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour PD-L1 anticorps (AA 39-191) (PE) (ABIN6935090)

Antigène: PD-L1 (CD274 (PD-L1))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PD-L1 est conjugé à/à la PE

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: PDL1-2746

Détail du produit anti-PD-L1 anticorps (PE)

Épitope: AA 39-191

Purification: Purified by Protein A/G

Immunogène: Recombinant fragment (around aa 39-191) of human CD274 (PD-L1) protein (exact sequence is proprietary)

Isotype: IgG2b kappa

Information d'application

Indications d'application:

Positive Control: Heart, Placenta, Spleen or Tonsil tissue (IF). Jurkat cells (FACS).

Known Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL),Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 100 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 4 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur PD-L1

Antigène: PD-L1 (CD274 (PD-L1))

Autre désignation: CD274

Sujet: PD-L1 is a checkpoint regulator in immune cells, it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in suppressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancer s ability to evade the immune system.

Poids moléculaire: 37-50kDa

ID gène: 29126

UniProt: Q9NZQ7

Pathways: Cancer Immune Checkpoints