Cyclin B2 anticorps

N° du produit ABIN6936587

Cet anticorps Souris Monoclonal détecte spécifiquement Cyclin B2 dans ELISA. Il présente une réactivité avec des échantillons de Humain, Souris, Rat et Xenopus laevis.

Aperçu rapide pour Cyclin B2 anticorps (ABIN6936587)

Antigène: Cyclin B2 (CCNB2)

Reactivité: Humain, Souris, Rat, Xenopus laevis

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cyclin B2 est non-conjugé

Application: ELISA

Clone: X29-2

Détail du produit anti-Cyclin B2 anticorps

Fonction: Cyclin B2 Antibody

Specificité: In eukaryotic cells, mitosis is initiated following the activation of a protein kinase known variously as maturation-promoting factor, M phase specific histone kinase or M-phase kinase. This protein kinase is composed of a catalytic subunit (Cdc2), a regulatory subunit (cyclin B) and a low molecular weight subunit (p13-Suc1). The Cdc/cyclin enzyme is subject to multiple levels of control, of which the regulation of the catalytic subunit by tyrosine phosphorylation is the best understood. Tyrosine phosphorylation inhibits the Cdc2/ cyclin B enzyme, and tyrosine dephosphorylation, occurring at the onset of mitosis, directly activates the pre-MPF complex. Evidence has established that B type cyclins not only act on M phase regulatory subunits of the Cdc2 protein kinase, but also activate the Cdc25A and Cdc25B endogenous tyrosine phosphatase, of which Cdc2 is the physiological substrate. The two B type cyclins, cyclin B1 and cyclin B2, have been shown to have distinct tissue distributions.

Réactivité croisée (Details): Mouse. Rat. Human. Xenopus laevis.

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant full-length Xenopus laevis Cyclin B2 protein

Isotype: IgG1, kappa

Information d'application

Indications d'application:

Known_Application: ELISA (For coating, order antibody without BSA), Optimal dilution for a specific application should be determined.

Positive_Control: HeLa cells. Human cervical tissue (IHC).

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur Cyclin B2

Antigène: Cyclin B2 (CCNB2)

Autre désignation: CCNB2

Sujet:

ccnb2, CycB2, Cyclin B2, G2 mitotic specific cyclin B2, HsT17299, MGC108931, MGC140694

HeLa cells. Human cervical tissue (IHC).

Poids moléculaire: 51kDa

ID gène: 9133, 194698

UniProt: O95067

Pathways: Cycle Cellulaire, M Phase