PD-L1 anticorps (AA 39-191)

N° du produit ABIN6936651

L’anticorps Souris Monoclonal anti-PD-L1 a été validé pour ELISA et Coat. Il convient pour détecter PD-L1 dans des échantillons de Humain.

Aperçu rapide pour PD-L1 anticorps (AA 39-191) (ABIN6936651)

Antigène: PD-L1 (CD274 (PD-L1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PD-L1 est non-conjugé

Application: ELISA, Coating (Coat)

Clone: PDL1-2741

Détail du produit anti-PD-L1 anticorps

Épitope: AA 39-191

Specificité: PD-L1 is a checkpoint regulator in immune cells, it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in suppressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancer s ability to evade the immune system.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant fragment of human CD274 protein (around aa39-191) (exact sequence is proprietary)

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Known_Application: ELISA (For coating, order antibody without BSA), ,Optimal dilution for a specific application should be determined.

Positive_Control: Heart, Placenta, Spleen or Tonsil.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur PD-L1

Antigène: PD-L1 (CD274 (PD-L1))

Autre désignation: CD274

Sujet: B7 homolog 1, B7-H1, CD274, PD-L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, Programmed cell death 1 ligand 1,PD-L1 / PDCD1LG1 / CD274 / B7-H1 (Cancer Immunotherapy Target)
Cellular localisation: Cell Surface and Cytoplasmic

Poids moléculaire: 37-50kDa

ID gène: 29126, 521989

UniProt: Q9NZQ7

Pathways: Cancer Immune Checkpoints