CD4 anticorps

N° du produit ABIN6936701

Cet anticorps Rat Monoclonal détecte spécifiquement CD4 dans FACS, IF et ELISA. Il présente une réactivité avec des échantillons de Souris.

Aperçu rapide pour CD4 anticorps (ABIN6936701)

Antigène: CD4

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CD4 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), ELISA

Clone: GK1-5

Détail du produit anti-CD4 anticorps

Fonction: CD4, Mouse (T-Cell Marker) Antibody

Specificité: CD4 is a member of the Ig superfamily, primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosine kinase, lck. CD4 is expressed by the majority of thymocytes, most helper T cells, a subset of NK-T cells and weakly by dendritic cells and macrophages. CD4 plays an important role in the development of T cells and is required for mature T cells to function optimally.This antibody blocks helper T cell responses to MHC class II antigens, including cytolysis, proliferation, allogeneic B cell help, and release of lymphokines.

Aucune reactivité croisée: Humain

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Mouse CTL clone V4

Isotype: IgG2b, kappa

Information d'application

Indications d'application:

Positive Control: Spleen, Thymus or Lymph Node.

Known Application: ELISA (For coating, order Ab without BSA & Azide), Neutralization Studies (Order Ab without BSA & Azide), Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur CD4

Antigène: CD4

Autre désignation: CD4

Sujet:

CD4 (L3T4), CD4, CD4+ Lymphocyte deficiency, included, Leu3, Ly-4, Lymphocyte antigen CD4, p55, T cell differentiation antigen L3T4, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4

Spleen, Thymus or Lymph Node.

Poids moléculaire: 55kDa

ID gène: 12504, 2209

UniProt: P06332

Pathways: TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events