CD4 anticorps

N° du produit ABIN6936701

Cet anticorps Rat Monoclonal détecte spécifiquement CD4 dans FACS, IF, ELISA, Neut et Coat. Il présente une réactivité avec des échantillons de Souris.

Aperçu rapide pour CD4 anticorps (ABIN6936701)

Antigène: CD4

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CD4 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), ELISA, Neutralization (Neut), Coating (Coat)

Clone: GK1-5

Détail du produit anti-CD4 anticorps

Aucune reactivité croisée: Humain

Purification: Purified by Protein A/G

Immunogène: Mouse CTL clone V4

Isotype: IgG2b kappa

Information d'application

Indications d'application:

Positive Control: Spleen, Thymus or Lymph Node.

Known Application: ELISA (For coating, order Ab without BSA & Azide), Neutralization Studies (Order Ab without BSA & Azide), Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Buffer: 10 mM PBS without BSA and without Azide.

Agent conservateur: Azide free

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months.

Date de péremption: 24 months

Détails sur CD4

Antigène: CD4

Autre désignation: CD4

Sujet: CD4 is a member of the Ig superfamily, primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosine kinase, lck. CD4 is expressed by the majority of thymocytes, most helper T cells, a subset of NK-T cells and weakly by dendritic cells and macrophages. CD4 plays an important role in the development of T cells and is required for mature T cells to function optimally.This antibody blocks helper T cell responses to MHC class II antigens, including cytolysis, proliferation, allogeneic B cell help, and release of lymphokines.

Poids moléculaire: 55kDa

ID gène: 12504

UniProt: P06332

Pathways: TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events