DNMT1 anticorps (AA 767-912)
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- Antigène Voir toutes DNMT1 Anticorps
- DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))
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Épitope
- AA 767-912
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp DNMT1 est non-conjugé
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Application
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Specificité
- This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE.
- Réactivité croisée (Details)
- Human.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogène
- Recombinant human DNMT1 protein fragment (around aa 767-912) (exact sequence is proprietary)
- Clone
- DNMT1-2061
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product DNMT1 Anticorps primaire
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- Indications d'application
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Raji cells. Tonsil or Placenta.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Agent conservateur
- Azide free
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Date de péremption
- 24 months
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- Antigène
- DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))
- Autre désignation
- DNMT1 (DNMT1 Produits)
- Synonymes
- anticorps cb1075, anticorps cb983, anticorps dmnt1, anticorps fb05h01, anticorps mta, anticorps wu:fb05h01, anticorps ADCADN, anticorps AIM, anticorps CXXC9, anticorps DNMT, anticorps HSN1E, anticorps MCMT, anticorps DDM2, anticorps DECREASED DNA METHYLATION 2, anticorps DMT01, anticorps DMT1, anticorps DNA METHYLTRANSFERASE, anticorps DNA METHYLTRANSFERASE 01, anticorps DNA METHYLTRANSFERASE 1, anticorps MET2, anticorps METHYLTRANSFERASE 2, anticorps METHYLTRANSFERASE I, anticorps METI, anticorps methyltransferase 1, anticorps Cxxc9, anticorps Dnmt, anticorps Dnmt1o, anticorps MTase, anticorps Met-1, anticorps Met1, anticorps MommeD2, anticorps m.MmuI, anticorps DNA methyltransferase 1, anticorps DNA (cytosine-5-)-methyltransferase 1, anticorps methyltransferase 1, anticorps DNA methyltransferase (cytosine-5) 1, anticorps DNMT1, anticorps dnmt1, anticorps Dnmt1, anticorps MET1
- Sujet
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ADCADN, AIM, CXXC-type zinc finger protein 9, CXXC9, DNA methyltransferase 1 (DNMT1), HSN1E, MCMT, Met1, MommeD2,DNMT1 / DNA Methyltransferase 1
Cellular localisation: Nuclear - Poids moléculaire
- 184kDa
- ID gène
- 1786, 202672
- UniProt
- P26358
- Pathways
- SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2
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