Recombinant Frataxin anticorps (AA 57-210)

N° du produit ABIN6937290

L’anticorps Souris Monoclonal anti-Frataxin a été validé pour ELISA et Coat. Il convient pour détecter Frataxin dans des échantillons de Humain.

Aperçu rapide pour Recombinant Frataxin anticorps (AA 57-210) (ABIN6937290)

Antigène: Frataxin (FXN)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Frataxin est non-conjugé

Application: ELISA, Coating (Coat)

Clone: RFXN-2124

Détail du produit anti-Frataxin anticorps

Épitope: AA 57-210

Specificité: Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), a human autosomal recessive neurodegenerative disease. Lack of Frataxin causes iron to accumulate in the mitochondrial matrix suggesting that Frataxin is involved in mitochondrial iron homeostasis and possibly in iron transport. Frataxin has an alpha-beta fold consisting of two helices flanking an antiparallel beta sheet.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant human Frataxin protein fragment (around aa 57-210) (exact sequence is proprietary)

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Known_Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA),Optimal dilution for a specific application should be determined.

Positive_Control: HepG2, HL-60 or HEK293 cells. Pancreas and Liver.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur Frataxin

Antigène: Frataxin (FXN)

Autre désignation: FXN

Sujet: CyaY, d-FXN, FARR, Frataxin mature form, Frataxin (81-210), FRDA, Friedreich ataxia protein, Fxn, i-FXN, m56-FXN, m78-FXN, m81-FXN, X25,Frataxin (Mitochondrial Marker)
Cellular localisation: Cytoplasmic (Mitochondria)

Poids moléculaire: 14kDa

ID gène: 2395, 20685

UniProt: Q16595

Pathways: Transition Metal Ion Homeostasis, Regulation of Cell Size