Recombinant Frataxin anticorps (AA 57-210)

N° du produit ABIN6937290

L’anticorps anti-Frataxin Monoclonal Souris est utilisé pour la détection de Frataxin dans des échantillons de Humain. Il a été validé pour ELISA.

Aperçu rapide pour Recombinant Frataxin anticorps (AA 57-210) (ABIN6937290)

Antigène: Frataxin (FXN)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Frataxin est non-conjugé

Application: ELISA

Clone: RFXN-2124

Détail du produit anti-Frataxin anticorps

Épitope: AA 57-210

Fonction: Recombinant Frataxin (Mitochondrial Marker) Antibody

Specificité: Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), a human autosomal recessive neurodegenerative disease. Lack of Frataxin causes iron to accumulate in the mitochondrial matrix suggesting that Frataxin is involved in mitochondrial iron homeostasis and possibly in iron transport. Frataxin has an alpha-beta fold consisting of two helices flanking an antiparallel beta sheet.

Réactivité croisée (Details): Human.

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant human Frataxin protein fragment (around aa 57-210) (exact sequence is proprietary)

Isotype: IgG1, kappa

Information d'application

Indications d'application:

Known_Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA),Optimal dilution for a specific application should be determined.

Positive_Control: HepG2, HL-60 or HEK293 cells. Pancreas and Liver.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur Frataxin

Antigène: Frataxin (FXN)

Autre désignation: FXN

Sujet:

CyaY, d-FXN, FARR, Frataxin mature form, Frataxin (81-210), FRDA, Friedreich ataxia protein, Fxn, i-FXN, m56-FXN, m78-FXN, m81-FXN, X25

HePG2, HL-60 or HEK293 cells. Pancreas and Liver.

Poids moléculaire: 14kDa

ID gène: 2395, 20685

UniProt: Q16595

Pathways: Transition Metal Ion Homeostasis, Regulation of Cell Size