Recombinant Frataxin anticorps (AA 57-210)
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- Antigène Voir toutes Frataxin (FXN) Anticorps
- Frataxin (FXN)
- Type d'anticorp
- Recombinant Antibody
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Épitope
- AA 57-210
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Frataxin est non-conjugé
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Application
- ELISA, Coating (Coat)
- Specificité
- Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), a human autosomal recessive neurodegenerative disease. Lack of Frataxin causes iron to accumulate in the mitochondrial matrix suggesting that Frataxin is involved in mitochondrial iron homeostasis and possibly in iron transport. Frataxin has an alpha-beta fold consisting of two helices flanking an antiparallel beta sheet.
- Réactivité croisée (Details)
- Human.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogène
- Recombinant human Frataxin protein fragment (around aa 57-210) (exact sequence is proprietary)
- Clone
- RFXN-2124
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product FXN Anticorps primaire
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- Indications d'application
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Known_Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA),Optimal dilution for a specific application should be determined.
Positive_Control: HepG2, HL-60 or HEK293 cells. Pancreas and Liver.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Agent conservateur
- Azide free
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Date de péremption
- 24 months
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- Antigène
- Frataxin (FXN)
- Autre désignation
- FXN (FXN Produits)
- Synonymes
- anticorps zgc:158218, anticorps LOC100284365, anticorps BcDNA:AT09528, anticorps CG8971, anticorps DFH, anticorps Dfh, anticorps Dmel\\CG8971, anticorps X25, anticorps dfh, anticorps CyaY, anticorps FA, anticorps FARR, anticorps FRDA, anticorps RGD1565754, anticorps Frda, anticorps frataxin, anticorps fxn, anticorps LOC100284365, anticorps TVAG_182150, anticorps fh, anticorps FTX1, anticorps FXN, anticorps Fxn
- Sujet
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CyaY, d-FXN, FARR, Frataxin mature form, Frataxin (81-210), FRDA, Friedreich ataxia protein, Fxn, i-FXN, m56-FXN, m78-FXN, m81-FXN, X25,Frataxin (Mitochondrial Marker)
Cellular localisation: Cytoplasmic (Mitochondria) - Poids moléculaire
- 14kDa
- ID gène
- 2395, 20685
- UniProt
- Q16595
- Pathways
- Transition Metal Ion Homeostasis, Regulation of Cell Size
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