Growth Hormone 1 anticorps (AA 58-187)

N° du produit ABIN6937314

Détail du produit anti-Growth Hormone 1 anticorps

Antigène: Growth Hormone 1 (GH1)

Épitope: AA 58-187

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Growth Hormone 1 est non-conjugé

Application: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Specificité: Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly).

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: A recombinant fragment (around aa58-187) of human Growth Hormone (GH) protein (exact sequence is proprietary)

Clone: GH-1371

Isotype: IgG2b kappa

Information d'application

Indications d'application:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: Pituitary cells. Human pituitary tissue (IHC).

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur Growth Hormone 1

Antigène: Growth Hormone 1 (GH1)

Autre désignation: GH1 (GH1 Produits)

Synonymes: anticorps GH, anticorps GH-N, anticorps GHN, anticorps IGHD1B, anticorps hGH-N, anticorps Gh1, anticorps GH1, anticorps gh, anticorps Gh, anticorps GH2, anticorps RNGHGP, anticorps ghl, anticorps gh-n, anticorps ghn, anticorps ighd1b, anticorps gh1, anticorps ghb-A, anticorps GHI, anticorps GHB3, anticorps growth hormone 1, anticorps growth hormone, anticorps somatotropin-like, anticorps somatotropin, anticorps growth hormone prepeptide, anticorps growth hormone 1 L homeolog, anticorps growth hormone 1 S homeolog, anticorps Somatotropin-1, anticorps GH1, anticorps Gh, anticorps GH, anticorps LOC100305005, anticorps Gh1, anticorps LOC100534452, anticorps LOC100232594, anticorps LOC100303681, anticorps gh1, anticorps LOC100356068, anticorps LOC100136588, anticorps gh1.L, anticorps gh1.S, anticorps LOC109081196

Sujet: GH-N, GH1, Growth hormone 1, HG1, hGH-N, IGHD1B, Pituitary growth hormone, RNGHGP, Somatotropin,Growth Hormone (Pituitary Marker)
Cellular localisation: Cytoplasmic

Poids moléculaire: 20kDa

ID gène: 2688, 655229

UniProt: P01241

Pathways: Signalisation NF-kappaB, Signalistation JAK/STAT, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process