Recombinant Growth Hormone 1 anticorps (AA 58-187)

N° du produit ABIN6937317

L’anticorps anti-Growth Hormone 1 Monoclonal Souris est utilisé pour la détection de Growth Hormone 1 dans des échantillons de Humain. Il a été validé pour IHC.

Aperçu rapide pour Recombinant Growth Hormone 1 anticorps (AA 58-187) (ABIN6937317)

Antigène: Growth Hormone 1 (GH1)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Growth Hormone 1 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: RGH-1450

Détail du produit anti-Growth Hormone 1 anticorps

Épitope: AA 58-187

Fonction: Recombinant Growth Hormone (Pituitary Marker) Antibody

Specificité: Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly).

Réactivité croisée (Details): Human.

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogène: A recombinant fragment (around aa58-187) of human Growth Hormone (GH) protein (exact sequence is proprietary)

Isotype: IgG1, kappa

Information d'application

Indications d'application:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: Pituitary cells. Human pituitary tissue (IHC).

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur Growth Hormone 1

Antigène: Growth Hormone 1 (GH1)

Autre désignation: GH1

Sujet:

GH, GH-N, GH1, GHN, Growth hormone 1, Growth hormone, Growth hormone, pituitary, HG1, hGH-N, IGHD1B, Pituitary growth hormone, RNGHGP, Somatotropin

Pituitary cells. Human pituitary tissue (IHC).

Poids moléculaire: 20kDa

ID gène: 2688, 655229

UniProt: P01241

Pathways: Signalisation NF-kappaB, Signalistation JAK/STAT, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process