HLA-ABC anticorps

N° du produit ABIN6937393

Cet anticorps anti-HLA-ABC est un anticorps Souris Monoclonal détectant HLA-ABC dans FACS et IF. Adapté pour Humain.

Aperçu rapide pour HLA-ABC anticorps (ABIN6937393)

Antigène: HLA-ABC

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HLA-ABC est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: 246-B8-E7

Détail du produit anti-HLA-ABC anticorps

Specificité: Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.

Réactivité croisée (Details): Human. Mouse. Non-Human primates.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Human peripheral blood leukocytes

Isotype: IgG2a kappa

Information d'application

Indications d'application:

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: THP-1 and Jurkat cells. Tonsil or lymph node.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur HLA-ABC

Antigène: HLA-ABC

Autre désignation: HLA-A, HLA-B, HLA-C

Sujet: HLA-A, HLA-B, HLA-C, HLA class 1A, HLA class 1B, HLA class 1C, Major histocompatibility complex, class I, A + B + C, MHC class I HLA-A, MHC class I HLA-B, MHC class I HLA-C, MHC HLA-ABC,HLA-ABC (MHC I)
Cellular localisation: Cell surface

Poids moléculaire: ~41kDa

ID gène: 3105, 3106, 3107

UniProt: P01889, P30443, P30499

Pathways: TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints