IGKC anticorps

N° du produit ABIN6937529

Détail du produit anti-IGKC anticorps

Antigène: IGKC (Immunoglobulin kappa Constant (IGKC))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IGKC est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Specificité: This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of kappa to lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Aucune reactivité croisée: Rat (Rattus)

Réactivité croisée (Details): Human. Does not react with Rat.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Human B-Lymphoma Cells

Clone: SPM508

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Known_Application: Flow Cytometry (0.5-2.0 μg/million cells), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: 293T, Raji or hPBL cells. Tonsil or Spleen.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur IGKC

Antigène: IGKC (Immunoglobulin kappa Constant (IGKC))

Autre désignation: IGKC (IGKC Produits)

Synonymes: anticorps HCAK1, anticorps IGKCD, anticorps Km, anticorps IGKC, anticorps Igk-C, anticorps immunoglobulin kappa constant, anticorps immunoglobulin kappa constant L homeolog, anticorps IGKC, anticorps LOC708048, anticorps igkc, anticorps igkc.L, anticorps Igkc

Sujet: HCAK1, Ig Kappa Chain C Region, IGKC, Immunoglobulin KM,Kappa Light Chain (B-Cell Marker)
Cellular localisation: Cell surface, cytoplasmic and secreted

Poids moléculaire: ~22.5kDa

ID gène: 3514, 449609

UniProt: P01601, P01834