Recombinant IL3RA anticorps (AA 26-171)
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- Antigène Voir toutes IL3RA Anticorps
- IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
- Type d'anticorp
- Recombinant Antibody
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Épitope
- AA 26-171
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp IL3RA est non-conjugé
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Application
- ELISA, Immunostaining (ISt), Coating (Coat), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Specificité
- CD123 is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudo-autosomal region on chromosomes X or Y.
- Réactivité croisée (Details)
- Human.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogène
- Recombinant fragment of human IL3RA protein (around aa 26-171) (exact sequence is proprietary)
- Clone
- IL3RA-2947R
- Isotype
- IgG
- Top Product
- Discover our top product IL3RA Anticorps primaire
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- Indications d'application
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Known_Application: ELISA (For coating, order antibody without BSA),Immunohistochemistry (Formalin-fixed) (0.25-0.5 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues is enhanced by heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0 for 45 min at 95°C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: THP-1, RPMI-8226 or HDLM-2 cells. Tonsil, Lymph Node or Stomach.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Agent conservateur
- Azide free
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Date de péremption
- 24 months
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- Antigène
- IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
- Autre désignation
- IL3RA (IL3RA Produits)
- Synonymes
- anticorps CD123, anticorps IL3R, anticorps IL3RAY, anticorps IL3RX, anticorps IL3RY, anticorps hIL-3Ra, anticorps CDw123, anticorps SUT-1, anticorps Cyrl, anticorps interleukin 3 receptor subunit alpha, anticorps interleukin 3 receptor, alpha chain, anticorps IL3RA, anticorps Il3ra
- Sujet
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CD123, hIL3Ra, IL-3R-alpha, IL-3RA, IL3RAX, IL3RAY, IL3RX, IL3RY, Interleukin-3 Receptor, alpha, Interleukin3 receptor, Interleukin3 receptor, Y-chromosomal,IL3RA / CD123 (Acute Myeloid Leukemia Marker)
Cellular localisation: Cell Surface and Cytoplasmic - Poids moléculaire
- ~70kDa
- ID gène
- 3563, 632790
- UniProt
- P26951
- Pathways
- Signalistation JAK/STAT
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