JUP anticorps

N° du produit ABIN6937613

Cet anticorps Souris Monoclonal détecte spécifiquement JUP dans WB, IF, IHC, FACS et ELISA. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Poulet, Chien, Boeuf (Vache) et Cat.

Aperçu rapide pour JUP anticorps (ABIN6937613)

Antigène: JUP (Junction Plakoglobin (JUP))

Reactivité: Humain, Souris, Rat, Poulet, Chien, Boeuf (Vache), Cat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp JUP est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA

Clone: 15F11

Détail du produit anti-JUP anticorps

Fonction: Catenin, gamma (Cardiomyocyte Marker) Antibody

Specificité: It recognizes a protein of 80-87 kDa, identified as gamma-catenin. The catenins (°™, æ, Á and 79oΩL) are ubiquitously expressed, cytoplasmic proteins that associate with E-cadherin at cellular junctions. Catenin/cadherin complexes play an important role in mediating cellular adhesion. °™ T-catenin, also referred to as VR22, is a 895-amino acid protein that is most abundantly expressed in cardio-myocytes and in the peritubular myoid cells of the testis. °™ T-catenin binds to °™ E-catenin as well as to æ-catenin, and it functions to inhibit Wnt signaling. CTNNA3, the gene that encodes for °™-T-catenin, is located on chromosome 10, and mutations in this gene show a strong correlation to late-onset Alzheimer s disease (LOAD) as well as to dilated cardiomyopathy.

Réactivité croisée (Details): Human. Mouse. Cat. Rat. Chicken. Cow. Dog.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant, full length chicken Catenin gamma protein

Isotype: IgG1, kappa

Information d'application

Indications d'application:

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: HeLa, SK-BR3, A431, HT20, 293, HepG2, A549 or MCF-7 cells. Skin.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur JUP

Antigène: JUP (Junction Plakoglobin (JUP))

Autre désignation: JUP

Sujet:

ARVD12, Catenin (cadherin-associated protein), gamma 80 kDa, Catenin gamma, CTNNG, Desmoplakin III, Desmoplakin-3, DP3, DPIII, Junction Plakoglobin, PDGB, PKGB

HeLa, SK-BR3 or MCF-7 cells.

Poids moléculaire: 80-87kDa

ID gène: 3728, 514174

UniProt: P14923

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location