Recombinant ADRP anticorps (AA 249-376)

N° du produit ABIN6938195

Détail du produit anti-ADRP anticorps

Antigène: ADRP (PLIN2) (Perilipin 2 (PLIN2))

Type d'anticorp: Recombinant Antibody

Épitope: AA 249-376

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ADRP est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Coating (Coat), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Specificité: Recognizes a protein of 48 kDa, which is identified as Adipophilin. It belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant fragment (around aa 249-376) of human Adipophilin (ADFP) protein (exact sequence is proprietary)

Clone: RADFP-1493

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Known_Application: ELISA (For coating, order Ab without BSA),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: Liver, adrenal gland or cerebellum (IHC).

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur ADRP

Antigène: ADRP (PLIN2) (Perilipin 2 (PLIN2))

Autre désignation: PLIN2 (PLIN2 Produits)

Synonymes: anticorps ADFP, anticorps ADRP, anticorps AA407157, anticorps ADPH, anticorps Adfp, anticorps Adrp, anticorps adfp, anticorps adrp, anticorps fatvg, anticorps MGC76047, anticorps adipophilin, anticorps PLIN2, anticorps DKFZp469F1012, anticorps perilipin-2, anticorps zgc:110411, anticorps perilipin 2, anticorps perilipin 2 L homeolog, anticorps adipophilin, anticorps perilipin-2, anticorps PLIN2, anticorps Plin2, anticorps plin2, anticorps plin2.L, anticorps LOC100304704, anticorps LOC100380740

Sujet: Adipophilin, ADFP, Adipose differentiation-related protein (ADRP), Perilipin-2 (PLIN2),Adipophilin / Perilipin-2 (Marker of Lipid Accumulation)
Cellular localisation: Cytoplasmic

Poids moléculaire: 48kDa

ID gène: 123, 3416

UniProt: Q99541

Pathways: Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism