PMEPA1 anticorps

N° du produit ABIN6938199

L’anticorps Souris Monoclonal anti-PMEPA1 a été validé pour IHC (f). Il convient pour détecter PMEPA1 dans des échantillons de Humain.

Aperçu rapide pour PMEPA1 anticorps (ABIN6938199)

Antigène: PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PMEPA1 est non-conjugé

Application: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Clone: PMEPA1-2697

Détail du produit anti-PMEPA1 anticorps

Specificité: PMEPA1 (prostate transmembrane protein, androgen induced 1 is a 287 amino acid single-pass membrane protein that contains WW-binding motifs and localizes to the cell membrane. Expressed at high levels in prostate, kidney and ovary, PMEPA1 interacts with NEDD4 and may play a role in regulating AR (androgen receptor) levels, specifically in prostate cells. Down regulation of PMEPA1 is observed in prostate tumors, suggesting that PMEPA1 may exhibit activity as a tumor suppressor. Overexpression of this protein may play a role in multiple types of cancer.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant full-length human PMEPA1 protein

Isotype: IgG kappa

Information d'application

Indications d'application:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: SKBR-3 cells. Prostate, Breast or Renal Cell Carcinoma.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur PMEPA1

Antigène: PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))

Autre désignation: PMEPA1

Sujet: PMEPA, PMEPA1, Prostate transmembrane protein, androgen induced 1, Solid tumor-associated 1 protein, STAG1, TMEPAI, Transmembrane prostate androgen-induced protein, Transmembrane, prostate androgen induced RNA,PMEPA1 / TMEPAI (Tumor Suppressor Oncoprotein)
Cellular localisation: Cell Surface and Cytoplasmic

Poids moléculaire: 32kDa

ID gène: 56937, 517155

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway