TGFA anticorps (C-Term)

N° du produit ABIN6938542

Cet anticorps anti-TGFA Monoclonal Souris (Clone SPM357) (ABIN6938542) détecte spécifiquement TGFA dans IF et FACS. L’anticorps est réactif avec des échantillons de Humain, Rat, Souris et Boeuf (Vache).

Aperçu rapide pour TGFA anticorps (C-Term) (ABIN6938542)

Antigène: TGFA (Transforming Growth Factor, alpha (TGFA))

Reactivité: Humain, Rat, Souris, Boeuf (Vache)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TGFA est non-conjugé

Application: Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: SPM357

Détail du produit anti-TGFA anticorps

Épitope: C-Term

Fonction: TGF-alpha (Transforming Growth Factor alpha) Antibody

Specificité: This antibody reacts with the C-terminus of TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. The staining with Ab-1 is completely blocked by the peptide used for raising this antibody. TGF (aa50) is a growth factor with 33 % homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.

Réactivité croisée (Details): Human. Cow. Rat. Mouse.

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogène: A 17-amino acid synthetic peptide from the carboxyl-terminus of rat TGFα.

Isotype: IgG1, kappa

Information d'application

Indications d'application:

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: Jurkat or Ramos cells. Testicular Carcinoma.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur TGFA

Antigène: TGFA (Transforming Growth Factor, alpha (TGFA))

Autre désignation: TGFA

Sujet:

EGF-like TGF, ETGF, TFGA, TGF Type 1, TGFA, Wa1, Waved 1

Jurkat or Ramos cells. Testicular Carcinoma.

Poids moléculaire: 6kDa

ID gène: 7039, 170009

UniProt: P01135

Pathways: Signalisation NF-kappaB, Signalisation RTK, EGFR Signaling Pathway