UCHL1 anticorps
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- Antigène Voir toutes UCHL1 Anticorps
- UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp UCHL1 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Specificité
- This MAb reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease.
- Réactivité croisée (Details)
- Human. Mouse. Rat. Cow. Pig. Dog.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogène
- Native UchL1 (PGP9.5) protein from brain
- Clone
- 31A3
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product UCHL1 Anticorps primaire
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- Indications d'application
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Known_Application: Flow Cytometry (1-2 μg/million cells),Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: T98G cells. Cerebellum.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Agent conservateur
- Azide free
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Date de péremption
- 24 months
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- Antigène
- UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))
- Autre désignation
- UCHL1 (UCHL1 Produits)
- Synonymes
- anticorps PARK5, anticorps PGP 9.5, anticorps PGP9.5, anticorps PGP95, anticorps Uch-L1, anticorps UCH-L1, anticorps UCHL1, anticorps cb358, anticorps wu:fc55h08, anticorps park5, anticorps pgp9.5, anticorps uch-l1, anticorps MGC132191, anticorps uchl1, anticorps AW822034, anticorps C88048, anticorps R75593, anticorps UCHL-1, anticorps gad, anticorps ubiquitin C-terminal hydrolase L1, anticorps ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase), anticorps ubiquitin C-terminal hydrolase L1 L homeolog, anticorps ubiquitin carboxyl-terminal esterase L1, anticorps ubiquitin carboxy-terminal hydrolase L1, anticorps UCHL1, anticorps uchl1, anticorps uchl1.L, anticorps LOC100304750, anticorps Uchl1
- Sujet
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Gracile Axonal Dystrophy, Neuron Cytoplasmic Protein 9.5, Park5, Parkinson Disease 5, PGP95, Protein Gene Product 9.5, Ubiquitin Carboxyl-terminal Esterase L1, Ubiquitin Carboxyl-terminal Hydrolase Isozyme L1, Ubiquitin Thioesterase L1, Ubiquitin Thiolesterase L1,PGP9.5 / UchL1 (pan-Neuronal Marker)
Cellular localisation: Cytoplasmic. Endoplasmic Reticulum membrane - Poids moléculaire
- 20-30kDa
- ID gène
- 7345, 518731
- UniProt
- P09936
- Pathways
- Feeding Behaviour
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