Recombinant CD21 anticorps (AA 44-196)

N° du produit ABIN6939181

Cet anticorps Souris Monoclonal détecte spécifiquement CD21 dans IHC et StM. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant CD21 anticorps (AA 44-196) (ABIN6939181)

Antigène: CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD21 est non-conjugé

Application: Immunohistochemistry (IHC), Staining Methods (StM)

Clone: RCR2-1952

Détail du produit anti-CD21 anticorps

Épitope: AA 44-196

Specificité: Recognizes a protein of 140 kDa, which is identified as the complement receptor 2(CR2)/CD21. This protein is expressed strongly on mature B cells, follicular dendritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny, CD21 appears after the pre-B-stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. CD21 expression is also gradually lost after stimulation of B cells in vitro.CD21 functions as receptor for C3d, C3dg and iC3b Complement components, for EBV and for IFNalpha.CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation.

Purification: Purified by Protein A/G

Immunogène: Recombinant fragment (around aa 44-196) of human CR2 (CD21) protein (exact sequence is proprietary)

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: WEHI-231 cells. Human tonsil (IHC).

Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur CD21

Antigène: CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))

Autre désignation: CR2

Poids moléculaire: 140kDa

ID gène: 1380

UniProt: P20023

Pathways: Système du Complément