Recombinant Frataxin anticorps (AA 57-210)

N° du produit ABIN6939443

Cet anticorps anti-Frataxin est un anticorps Souris Monoclonal détectant Frataxin dans ELISA et Coat. Adapté pour Humain.

Aperçu rapide pour Recombinant Frataxin anticorps (AA 57-210) (ABIN6939443)

Antigène: Frataxin (FXN)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Frataxin est non-conjugé

Application: ELISA, Coating (Coat)

Clone: RFXN-2124

Détail du produit anti-Frataxin anticorps

Épitope: AA 57-210

Purification: Purified by Protein A/G

Immunogène: Recombinant human Frataxin protein fragment (around aa 57-210) (exact sequence is proprietary)

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: HepG2, HL-60 or HEK293 cells. Pancreas and Liver.

Known Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA),Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur Frataxin

Antigène: Frataxin (FXN)

Autre désignation: FXN

Sujet: Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), a human autosomal recessive neurodegenerative disease. Lack of Frataxin causes iron to accumulate in the mitochondrial matrix suggesting that Frataxin is involved in mitochondrial iron homeostasis and possibly in iron transport. Frataxin has an alpha-beta fold consisting of two helices flanking an antiparallel beta sheet.

Poids moléculaire: 14kDa

ID gène: 2395

UniProt: Q16595

Pathways: Transition Metal Ion Homeostasis, Regulation of Cell Size