HLA-ABC anticorps

N° du produit ABIN6939617

Cet anticorps Souris Monoclonal détecte spécifiquement HLA-ABC dans FACS et IF. Il présente une réactivité envers Humain, Souris et Non-Human Primate.

Aperçu rapide pour HLA-ABC anticorps (ABIN6939617)

Antigène: HLA-ABC

Reactivité: Humain, Souris, Non-Human Primate

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HLA-ABC est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: 246-B8-E7

Détail du produit anti-HLA-ABC anticorps

Specificité: Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.

Purification: Purified by Protein A/G

Immunogène: Human peripheral blood leukocytes

Isotype: IgG2a kappa

Information d'application

Indications d'application:

Positive Control: THP-1 and Jurkat cells. Tonsil or lymph node.

Known Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur HLA-ABC

Antigène: HLA-ABC

Autre désignation: HLA-A, HLA-B, HLA-C

Poids moléculaire: ~41kDa

ID gène: 3105, 3106, 3107

UniProt: P01889, P30443, P30499

Pathways: TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints