Recombinant IGF1 anticorps

N° du produit ABIN6939702

Cet anticorps Lapin Monoclonal détecte spécifiquement IGF1 dans WB, IHC, ELISA, IF, FACS et Coat. Il présente une réactivité avec des échantillons de Humain, Souris, Rat et Lapin.

Aperçu rapide pour Recombinant IGF1 anticorps (ABIN6939702)

Antigène: IGF1 (Insulin-Like Growth Factor 1 (IGF1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat, Lapin

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp IGF1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Coating (Coat)

Clone: IGF1-2872R

Détail du produit anti-IGF1 anticorps

Specificité: This antibody is specific to Insulin-like Growth Factor (IGF-1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF-1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF-1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.

Purification: Purified by Protein A/G

Immunogène: Recombinant full-length human IGF-1 protein

Isotype: IgG

Information d'application

Indications d'application:

Positive Control: Breast, Thyroid or Colon Cancers (IHC). K562 cells (FACS). IGF-1 recombinant protein (WB).

Known Application: ELISA (For coating, order antibody without BSA), Flow Cytometry (1-2 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur IGF1

Antigène: IGF1 (Insulin-Like Growth Factor 1 (IGF1))

Autre désignation: IGF1

Poids moléculaire: ~7.6kDa

ID gène: 3479

UniProt: P05019

Pathways: Signalisation RTK, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Hormone Activity, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Activated T Cell Proliferation, Positive Regulation of fat Cell Differentiation